Omega-3 Does Not Prevent Atrial Fibrillation

Omega-3 Does Not Prevent Atrial Fibrillation.


Omega-3 fatty acid supplements don't chop back on recurrences of atrial fibrillation, a species of anomalous heartbeat that can cause stroke, renewed exploration suggests. "We now have reliable data that they don't work for most patients with AF atrial fibrillation ," said Dr Peter R Kowey, flex founder of a scrutiny appearing in the Dec 1, 2010 discharge of the Journal of the American Medical Association that is also scheduled to be presented Monday at the American Heart Association's annual assembly in Chicago. "Although we can't count out the feasibility of efficacy in sicker AF patients, it would be steadfastly to believe that it would peg away in that population and not in healthier patients penis enlarge unani india. So for pragmatic purposes, yes, this is the end of the line in AF".



This study, the largest of its kind, looked at patients with AF who were otherwise healthy. "We cannot answer there is any convincing basis of a place for omega-3 in the prevention of atrial fibrillation," added Dr Ranjit Suri, chief honcho of the Electrophysiology Service and Cardiac Arrhythmia Center at Lenox Hill Hospital in New York City, who was not knotty with the trial pret dapoxetine. The studio was funded by GlaxoSmithKline.



Omega-3 fatty acids, which are found in fatty fish such as salmon and albacore tuna, had showed some foretell in preventing verve contagion in earlier trials. Of the add up to 663 outpatient participants, 542 had paroxysmal atrial fibrillation, which appears in a flash and resolves on its own, and 121 had unending atrial fibrillation, which needs treatment.



Participants were randomized to come by either a placebo or 8 grams of omega-3 supplements regular for the inception week, followed by 4 grams a heyday for the uneaten 23 weeks of the trial. The doses cast-off in the swatting are available only by prescription and are "higher than doses in days published in studies," said Dr Robert Block, a cardiologist and aide-de-camp professor of community and prevention medicine at the University of Rochester Medical Center.



At the end of six months, 46 percent of those in the placebo assemble and 52 percent of those fetching omega-3 supplements accomplished recurrences. The numbers of paroxysmal AF patients in the placebo and curing groups who had AF recurrences were about come up to (48 percent and 52 percent, respectively), the investigators found.



In patients with unswerving AF, more patients in the omega-3 arm had recurrences than in the placebo put together (50 percent and 33 percent, respectively). But experts haven't ruled out a admissible lines for omega-3 in other types of patients, such as those with callousness failure. "Our facts do not say to other cardiac indications," said Kowey, who is president of the Main Line Health Heart Center and a professor of pharmaceutical and clinical pharmacology at Jefferson Medical College in Philadelphia.



So "There has been conflicting evidence there as well and a radiantly desideratum for exhaustive studies identical to ours in those indications". "Omega-3 may be beneficial in patients with high triglycerides and bad overall cholesterol profiles or masses prone to electric storms in the spunk who are at risk of sudden death," said Suri. Block recommends that patients with cardiovascular infection have a bite two servings of smarmy fish weekly, or three over-the-counter omega-3 capsules a day bode hyprogel egypt. In those with no cardiovascular disease, "there is no field authoritative benefit," but they still might also want to dine fish regularly, he said.