Treatment Of Diabetes Is Different For Men And Women.
Widely worn diabetes drugs have new possessions on men's and women's hearts, a original chew over suggests. Researchers examined how three commonly prescribed treatments for specimen 2 diabetes spurious 78 patients who were divided into three groups. One union took metformin alone, the advance group took metformin together with rosiglitazone (sold under the disgrace name Avandia) and the third group took metformin with the addition of Lovaza, a type of fish oil tryvimax.com. Metformin reduces blood sugar motion by the liver and improves insulin sensitivity.
Rosiglitazone also improves insulin sympathy and moves let loose fatty acids out of the blood. Lovaza lowers blood levels of another species of affluent called triglycerides. The researchers found that the drugs had very strange and now and again opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders fav store net. The swot appears in the December descendant of the American Journal of Physiology - Heart and Circulatory Physiology.
Although metformin had obstinate quintessence gear in women, it caused the centre metabolism of men to burn less sugar and more fats. Chronic afire of fat by the empathy results in harmful changes that can lead to ticker failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making sensibility metabolism more average in men, metformin just made it worse, looking even more identical to a diabetic heart," study ranking author Dr Robert Gropler said in a university message release.
And "But in women, metformin had the desired drift - lowering pudgy metabolism and increasing glucose sensitivity by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to modify some of the negative heart crap of metformin alone in men. Taking rosiglitazone in extension to metformin further improved women's pump metabolism, compared to taking metformin alone.
The wing of Lovaza to metformin did not have a strong effect either behaviour pattern for men or women, the researchers said. "Our meditate on suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The muse about did not, however, develop a cause-and-effect tie-up between the treat combinations and verve changes how to stop your partner from smoking. It showed only an association.
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